Clomiphene citrate: results and medical recommendations

With clomiphene citrate (Clomiphene citrate)

Synonyms:

  • Clomid,
  • Clomiphene,
  • Clomiphene citrate
  • Clomid,
  • Pergotaym,
  • Serpafar

Pharmachologic effect

It stimulates the production of gonadotropins and ovulation; It has a strong anti-estrogen effect.

Indications for use

Stimulation of ovulation; anovulatory disorders of pituitary and hypothalamic origin secondary amenorrhea of ??different etiology (except giperprolaktinovoy and ovarian forms) with androgen deficiency and oligospermia in men, oligomenorrhea, amenorrhea postkontratseptivnaya.

Dosage and administration

In women, treatment is initiated with the 5th day of the menstrual cycle and is carried on for 5 days; into 50 mg (0.05 g), 1 day (before bedtime). In the absence of the effect of increasing the dose to 75-100 mg or increase the duration of the course to 10 days. Heading dose should not exceed 500 mg. Men 50 mg 1-2 times a day for 3-4 months under the systematic control sperm. Details

Side effect

Ovarian hyperstimulation (abdominal pain, flatulence), monorragiya may cystic enlargement of the ovaries; during treatment can occur multiple pregnancy; nausea, diarrhea, flushing, dizziness, dermatitis, blurred vision. With the development of these phenomena should stop taking the drug. Men can be pain in the testicles.

Contraindications

Benign or malignant tumors, pregnancy. Diseases of the nervous system, liver; bleeding, ovarian cysts, pituitary function violation. Contraindicated in those whose activities require increased attention and quick response. Read more

Product form

Tablets of 0.05 grams per pack – 10 pieces or 30 pieces.

Storage conditions

List B. In the dark place in tightly closed containers.

Shelf life 2 years.